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DxMedical Cloud™
Technology for overwhelmingly high-speed detection from all over the world.
We use our unique algorithm to deliver the latest technology and product information from around the world in real time.
Explore the future of healthcare with carefully selected information.
How We Help You To Empower Your Business
POINT 1.
Quickly Deliver Technical Information
We deliver what you seek quickly and in a short time from technical information from all over the world
POINT 2.
Briefly to the Point
A wealth of detailed features makes it easy to understand the main points
POINT 3.
Help with Growth Strategies
The report is also packed with analytical information from the perspective of growth and long-term strategies for business use
Catch Up on the Latest Information
from Around the World
In today's world, where the world is networked by advances in information technology and numerous technologies are evolving at an astonishing speed, it is extremely difficult to manually collect and manage the vast amount of information from all over the world.
DxMedical Cloud™ collects and analyzes professional information from around the world and uses proprietary algorithms to quickly and accurately deliver the information you seek and the best information for you.
search
Quick search in Japanese
You can quickly search for information published in various languages around the world in Japanese. Get the information you need from the vast amount of information available worldwide without having to worry about language barriers.
emergency
Recommendations for You
DxMedical Cloud's proprietary algorithms predict the best information based on your interests and preferences and deliver it to you daily. Stay one step ahead of the curve without the hassle of searching, maximizing your daily information gathering.
Fuzzy Search
In addition to word matching, the search by similar and related keywords delivers news that is often missed due to paraphrasing and shaky spelling.
Japanese Localization
By providing titles and summaries of information from around the world in Japanese, it streamlines the process of “finding” the information you want from search results.
Academic Search
For researchers and professionals, you can search and browse more specialized information, such as articles submitted to journals by universities and research institutes.
More features to enhance your team's productivity
Bookmark
Instantly save and manage information that you like or want to look at later because you don't have time, with the bookmark function. You can access the information you need without hassle, saving you a great deal of time and effort.
Note Editor
Simple and intuitive operation allows you to quickly consolidate all information into a notebook and organize information efficiently. It can be used as a powerful tool for effective information sharing.
Information sharing
A wide range of information sharing tools are available, including chat and note sharing functions. We support information sharing with your team in all situations, from casual information sharing to organizing information in teams.
Collaboration
Provides task management functions specifically designed to make information gathering and sharing more efficient. In addition to regular task management functions, this useful tool supports information gathering and sharing, improving the productivity of the entire team.
DigitalMedical Open Innovation
BrainEnergy produce DigitalMedical open innovation from Tokyo, where you can experience the intersection of cool and passionate design and technology.
Transform Your Business With Cloud
Looking for the Future of Health Care
OUR TECHNOLOGY HELPS YOUR BUSINESS
Our technology will help your business
Technology
Biotech start-up PeelON secures $1 million to scale compostable packaging for fruits and vegetables
PeelON, a biotech start-up specialising in biodegradable, compostable packaging for fresh produce, has raised $1 million in a seed funding round. The round was led by DeepTech-focused VC, growX ventures, with participation from Boston Venture Group, Clean Energy Venture Group, and Climate Angels. PeelON, which develops plant-based films that extend the shelf life of fruits and vegetables, operates on a B2B model, working with farmers, exporters, and retailers to eliminate single-use plasti
A service that utilizes AI to visualize sleep quality and contribute to reducing medical expenses Based on unique data analysis, promotes behavioral changes in sleep
JMDC Co., Ltd. (Headquarters: Minato-ku, Tokyo; President and CEO: Ryo Noguchi; hereinafter “JMDC”) has released “Pep Up Sleep,” a feature that visualizes sleep quality and promotes improvement, as part of its PHR service “Pep Up” on July 7, 2025. In recent years, the decline in sleep quality among working-age individuals has emerged as a critical health issue, increasing the risk of chronic diseases such as depression and hypertension, and contributing to rising medical costs. “Pep Up Sleep” utilizes sleep data collected from wearable devices, combined with health check-up questionnaires, to provide a sleep score based on subjective restfulness and actionable improvement recommendations.
Measuring histamine dynamics during eating behavior using a new biosensor, HisLightG
Histamine is involved in the regulation of food intake, but its dynamics during individual feeding episodes remain unclear. In this study, we combined a novel genetically encoded histamine sensor, HisLightG, with fiber photometry to measure histamine release in two hypothalamic regions, the dorsolateral nucleus (VMH) and the paraventricular nucleus (PVH) of the hypothalamus.Male mice were tested under different conditions to evaluate the effects of fasting, time of day, or calorie content of the administered solution on histamine fluctuations. Results showed that histamine levels changed rapidly in response to feeding, and histamine fluctuations were influenced by experimental conditions. Specifically, responses were slightly smaller when the test solution was sucrose or during the light phase.Additionally, while histamine returned to baseline levels in the PVH, it remained below baseline levels for over 10 seconds after feeding cessation in the VMH. Furthermore, administration of histamine precursors (L-histidine) reduced lick counts at multiple sucrose concentrations. These results suggest that histamine activity is rapidly regulated during feeding episodes and provide insights into the role of histamine in appetite suppression.
Treatment of insomnia in the elderly: BZD use reduces sleep quality
The frequent use of benzodiazepine-like drugs (BZD) and benzodiazepine receptor agonists (BZRA) in the treatment of insomnia in the elderly has been a cause for concern, with reports indicating that chronic use may have adverse effects on sleep regulation and cognitive function. In particular, the effects on NREM slow-wave activity (SO) and spindle waves remain poorly understood.A study by Loic Barbaux and colleagues at Concordia University in Canada investigated the effects of chronic BZD/BZRA use on memory in the elderly.
Thai researchers develop nanoemulsion containing magenta plant extract useful for anti-aging
A university research team has developed a stable water-in-oil nanoemulsion applicable to anti-aging cosmetics using Peristrophe bivalvis (magenta plant), a traditional medicinal plant. Components extracted from the leaves of this plant have been confirmed to exhibit strong antioxidant effects, glycation inhibition, and suppression of lipid peroxidation, and have been shown to be non-toxic to human skin fibroblasts.Three solvents (WE, EE, and AE) were used for extraction, with the EE extract showing the highest phenol and flavonoid content, as well as high antioxidant activity and safety. The nanoemulsion was formulated with an emulsifier ratio of 2:1 to enhance the delivery efficiency of active ingredients and product stability. The nanoemulsion using EE and WE extracts maintained stability and was concluded to be suitable for product development.Future studies should focus on the identification and quantification of specific bioactive molecules and the verification of their in vivo effects.
Battery life doubled to 10 years – Treatment device for overactive bladder launched by Medtronic Japan
On the 13th, Medtronic Japan announced the launch of sales of “InterStimX,” a non-rechargeable stimulation device for sacral nerve stimulation therapy, which suppresses the activity of the sacral nerves related to bladder and anal movements through electrical stimulation to treat overactive bladder and fecal incontinence. A key feature is its battery life of approximately 10 years with standard use, twice as long as previous products.The device, implanted into the body, delivers electrical stimulation to the sacral nerves, aiming to improve symptoms of overactive bladder and fecal incontinence.
Wearable Sensors Provide Real-Time Measurements of Sweat Rate and Electrolytes and Metabolites in Sweat
Researchers developed wearable skin sensors that can detect what’s in a person’s sweat. Using the sensors, monitoring perspiration could bypass the need for more invasive procedures like blood draws and provide real-time updates on health problems such as dehydration or fatigue. The sensor design can be rapidly manufactured using a roll-to-roll processing technique that essentially prints the sensors onto a sheet of plastic. The sensors were used to monitor the sweat rate and the electrolytes and metabolites in sweat from volunteers who were exercising and others who were experiencing chemically induced perspiration. The sensors are reliable, reproducible, and can be fabricated to scale so multiple sensors can be placed in different spots of the body.
The Spanish innovators fighting food waste – and food-poisoning – with smart labels
Food waste is a critical global problem, costing billions annually and contributing significantly to environmental damage. In the European Union alone, over 59 million tonnes of food are discarded every year – a staggering 132 kilograms per person – while millions suffer from foodborne illnesses. Addressing these challenges, three young Spanish entrepreneurs, Pilar Granado, Pablo Sosa Domínguez, and Luis Chimeno, have developed smart biodegradable labels that detect bacterial growth on food and signal freshness in real time. This breakthrough has earned them a place among the top 10 selected innovators in the Young Inventors Prize 2025.
SINGAPORE'S REBEE HEALTH RAISES INVESTMENT FROM 1337 VENTURES TO EXPAND DIGITAL PHYSIOTHERAPY SOLUTIONS
Singapore-based health tech firm Rebee Health has raised investment from Malaysia-based venture capital firm 1337 Ventures to expand digital physiotherapy solutions. 1337 Ventures said in a statement on Wednesday that recognizing Rebee Health’s potential to reshape rehabilitation, 1337 Ventures has invested in the startup through its 1337 Capital 1, furthering its commitment to funding disruptive technology in healthcare. With this funding, Rebee Health aims to expand its wearable rehabilitation solutions to more hospitals, clinics, and direct consumers, develop artificial intelligence (AI)-driven rehabilitation to enhance patient engagement and recovery, and strengthen data insights for remote decision-making to improve patient outcomes and reduce costs.
3D-Printed Device Turns Motion Into Power
researchers at Boise State University have developed a TENG that is made with biocompatible and eco-friendly materials. Furthermore, their energy harvesters can be fabricated with just a 3D printer. These factors could make energy harvesting technologies not only more practical, but also easier and less costly for developers to experiment with. The team has created a fully printed TENG using a novel composite ink composed of poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) (PVBVA) and Ti₃C₂Tₓ MXene nanosheets. This formulation enables additive manufacturing of high-performance, skin-compatible devices that can be directly integrated into wearables.
German beauty startup is looking for a contract manufacturer for high-quality, vegan lip products under a commercial agreement
The German startup is specialised in the development and sales of high-quality, vegan lip products designed for a style-conscious, diverse Gen Z community. They are looking for a manufacturing partner, specialised in lipstick and lip balm production, for a private label production. A long-term collaboration under a commercial agreement is desired.
Analysis of the characteristics of the gut microbiota of elderly Japanese patients with sarcopenia
A research group led by Professor Daisuke Asaoka, Professor Toshihiko Oka, and Professor Nobuhiro Sato of Juntendo University analyzed the gut microbiota of elderly men and women (398 individuals) who visited the Department of Gastroenterology at Juntendo Tokyo Koto Geriatric Medical Center.In male sarcopenia patients, a decrease in gut microbiota diversity and a reduction in the abundance of bacterial groups associated with butyrate production were confirmed. These bacterial groups showed a positive correlation with muscle-related indicators, suggesting a potential association with impaired muscle function.In contrast, no such association was observed in female sarcopenia patients, suggesting that the effects of gut microbiota on muscle function may differ between men and women. These findings suggest that controlling gut microbiota may contribute to sarcopenia prevention, highlighting the importance of dietary interventions and other strategies to maintain gut microbiota health. This study was published online in the journal Nutrients on May 21, 2025.
Moving toward circular agriculture thanks to nutrient separation from manure
Research is underway to develop a circular system for agriculture. Livestock manure contains nutrients such as nitrogen (N), phosphorus (P), and potassium (K), and excessive use of these nutrients can have a negative impact on the environment. As a result, farmers are unable to spread all manure on their land due to environmental regulations and must use synthetic fertilizers as an alternative. However, the production of synthetic fertilizers requires a large amount of energy and has a significant environmental impact.To address this contradiction, researchers are developing methods to separate nitrogen and potassium from manure and convert them into reusable forms. Dr. Marit van der Wal is conducting research using membrane technology to separate these nutrients and enable farmers to use them in precise quantities. This technology is expected to make agriculture sustainable while adhering to environmental regulations.
DxMedical Cloud™
Technology for overwhelmingly high-speed detection from all over the world.
We use our unique algorithm to deliver the latest technology and product information from around the world in real time.
Explore the future of healthcare with carefully selected information.
How We Help You To Empower Your Business
POINT 1.
Quickly Deliver Technical Information
We deliver what you seek quickly and in a short time from technical information from all over the world
POINT 2.
Briefly to the Point
A wealth of detailed features makes it easy to understand the main points
POINT 3.
Help with Growth Strategies
The report is also packed with analytical information from the perspective of growth and long-term strategies for business use
DigitalMedical Open Innovation
デジタル・メディカル・オープンイノベーション
BrainEnergy produce DigitalMedical open innovation from Tokyo, where you can experience the intersection of cool and passionate design and technology.
Transform Your Business With Cloud
Looking for the Future
of Health Care
OUR TECHNOLOGY HELPS
YOUR BUSINESS
Our technology will help your business
Technology
Biotech start-up PeelON secures $1 million to scale compostable packaging for fruits and vegetables
PeelON, a biotech start-up specialising in biodegradable, compostable packaging for fresh produce, has raised $1 million in a seed funding round. The round was led by DeepTech-focused VC, growX ventures, with participation from Boston Venture Group, Clean Energy Venture Group, and Climate Angels. PeelON, which develops plant-based films that extend the shelf life of fruits and vegetables, operates on a B2B model, working with farmers, exporters, and retailers to eliminate single-use plasti
businessline
A service that utilizes AI to visualize sleep quality and contribute to reducing medical expenses Based on unique data analysis, promotes behavioral changes in sleep
JMDC Co., Ltd. (Headquarters: Minato-ku, Tokyo; President and CEO: Ryo Noguchi; hereinafter “JMDC”) has released “Pep Up Sleep,” a feature that visualizes sleep quality and promotes improvement, as part of its PHR service “Pep Up” on July 7, 2025. In recent years, the decline in sleep quality among working-age individuals has emerged as a critical health issue, increasing the risk of chronic diseases such as depression and hypertension, and contributing to rising medical costs. “Pep Up Sleep” utilizes sleep data collected from wearable devices, combined with health check-up questionnaires, to provide a sleep score based on subjective restfulness and actionable improvement recommendations.
JMDC
Measuring histamine dynamics during eating behavior using a new biosensor, HisLightG
Histamine is involved in the regulation of food intake, but its dynamics during individual feeding episodes remain unclear. In this study, we combined a novel genetically encoded histamine sensor, HisLightG, with fiber photometry to measure histamine release in two hypothalamic regions, the dorsolateral nucleus (VMH) and the paraventricular nucleus (PVH) of the hypothalamus.Male mice were tested under different conditions to evaluate the effects of fasting, time of day, or calorie content of the administered solution on histamine fluctuations. Results showed that histamine levels changed rapidly in response to feeding, and histamine fluctuations were influenced by experimental conditions. Specifically, responses were slightly smaller when the test solution was sucrose or during the light phase.Additionally, while histamine returned to baseline levels in the PVH, it remained below baseline levels for over 10 seconds after feeding cessation in the VMH. Furthermore, administration of histamine precursors (L-histidine) reduced lick counts at multiple sucrose concentrations. These results suggest that histamine activity is rapidly regulated during feeding episodes and provide insights into the role of histamine in appetite suppression.
National Institutes of Health (NIH)
Treatment of insomnia in the elderly: BZD use reduces sleep quality
The frequent use of benzodiazepine-like drugs (BZD) and benzodiazepine receptor agonists (BZRA) in the treatment of insomnia in the elderly has been a cause for concern, with reports indicating that chronic use may have adverse effects on sleep regulation and cognitive function. In particular, the effects on NREM slow-wave activity (SO) and spindle waves remain poorly understood.A study by Loic Barbaux and colleagues at Concordia University in Canada investigated the effects of chronic BZD/BZRA use on memory in the elderly.
CareNet
Thai researchers develop nanoemulsion containing magenta plant extract useful for anti-aging
A university research team has developed a stable water-in-oil nanoemulsion applicable to anti-aging cosmetics using Peristrophe bivalvis (magenta plant), a traditional medicinal plant. Components extracted from the leaves of this plant have been confirmed to exhibit strong antioxidant effects, glycation inhibition, and suppression of lipid peroxidation, and have been shown to be non-toxic to human skin fibroblasts.Three solvents (WE, EE, and AE) were used for extraction, with the EE extract showing the highest phenol and flavonoid content, as well as high antioxidant activity and safety. The nanoemulsion was formulated with an emulsifier ratio of 2:1 to enhance the delivery efficiency of active ingredients and product stability. The nanoemulsion using EE and WE extracts maintained stability and was concluded to be suitable for product development.Future studies should focus on the identification and quantification of specific bioactive molecules and the verification of their in vivo effects.
Cosmetics Design Asia
Battery life doubled to 10 years – Treatment device for overactive bladder launched by Medtronic Japan
On the 13th, Medtronic Japan announced the launch of sales of “InterStimX,” a non-rechargeable stimulation device for sacral nerve stimulation therapy, which suppresses the activity of the sacral nerves related to bladder and anal movements through electrical stimulation to treat overactive bladder and fecal incontinence. A key feature is its battery life of approximately 10 years with standard use, twice as long as previous products.The device, implanted into the body, delivers electrical stimulation to the sacral nerves, aiming to improve symptoms of overactive bladder and fecal incontinence.
薬事日報
Wearable Sensors Provide Real-Time Measurements of Sweat Rate and Electrolytes and Metabolites in Sweat
Researchers developed wearable skin sensors that can detect what’s in a person’s sweat. Using the sensors, monitoring perspiration could bypass the need for more invasive procedures like blood draws and provide real-time updates on health problems such as dehydration or fatigue. The sensor design can be rapidly manufactured using a roll-to-roll processing technique that essentially prints the sensors onto a sheet of plastic. The sensors were used to monitor the sweat rate and the electrolytes and metabolites in sweat from volunteers who were exercising and others who were experiencing chemically induced perspiration. The sensors are reliable, reproducible, and can be fabricated to scale so multiple sensors can be placed in different spots of the body.
Tech Briefs
The Spanish innovators fighting food waste – and food-poisoning – with smart labels
Food waste is a critical global problem, costing billions annually and contributing significantly to environmental damage. In the European Union alone, over 59 million tonnes of food are discarded every year – a staggering 132 kilograms per person – while millions suffer from foodborne illnesses. Addressing these challenges, three young Spanish entrepreneurs, Pilar Granado, Pablo Sosa Domínguez, and Luis Chimeno, have developed smart biodegradable labels that detect bacterial growth on food and signal freshness in real time. This breakthrough has earned them a place among the top 10 selected innovators in the Young Inventors Prize 2025.
euronews
SINGAPORE'S REBEE HEALTH RAISES INVESTMENT FROM 1337 VENTURES TO EXPAND DIGITAL PHYSIOTHERAPY SOLUTIONS
Singapore-based health tech firm Rebee Health has raised investment from Malaysia-based venture capital firm 1337 Ventures to expand digital physiotherapy solutions. 1337 Ventures said in a statement on Wednesday that recognizing Rebee Health’s potential to reshape rehabilitation, 1337 Ventures has invested in the startup through its 1337 Capital 1, furthering its commitment to funding disruptive technology in healthcare. With this funding, Rebee Health aims to expand its wearable rehabilitation solutions to more hospitals, clinics, and direct consumers, develop artificial intelligence (AI)-driven rehabilitation to enhance patient engagement and recovery, and strengthen data insights for remote decision-making to improve patient outcomes and reduce costs.
tnglobal
3D-Printed Device Turns Motion Into Power
researchers at Boise State University have developed a TENG that is made with biocompatible and eco-friendly materials. Furthermore, their energy harvesters can be fabricated with just a 3D printer. These factors could make energy harvesting technologies not only more practical, but also easier and less costly for developers to experiment with. The team has created a fully printed TENG using a novel composite ink composed of poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) (PVBVA) and Ti₃C₂Tₓ MXene nanosheets. This formulation enables additive manufacturing of high-performance, skin-compatible devices that can be directly integrated into wearables.
hackster.io
German beauty startup is looking for a contract manufacturer for high-quality, vegan lip products under a commercial agreement
The German startup is specialised in the development and sales of high-quality, vegan lip products designed for a style-conscious, diverse Gen Z community. They are looking for a manufacturing partner, specialised in lipstick and lip balm production, for a private label production. A long-term collaboration under a commercial agreement is desired.
Enterprise Europe Network
Analysis of the characteristics of the gut microbiota of elderly Japanese patients with sarcopenia
A research group led by Professor Daisuke Asaoka, Professor Toshihiko Oka, and Professor Nobuhiro Sato of Juntendo University analyzed the gut microbiota of elderly men and women (398 individuals) who visited the Department of Gastroenterology at Juntendo Tokyo Koto Geriatric Medical Center.In male sarcopenia patients, a decrease in gut microbiota diversity and a reduction in the abundance of bacterial groups associated with butyrate production were confirmed. These bacterial groups showed a positive correlation with muscle-related indicators, suggesting a potential association with impaired muscle function.In contrast, no such association was observed in female sarcopenia patients, suggesting that the effects of gut microbiota on muscle function may differ between men and women. These findings suggest that controlling gut microbiota may contribute to sarcopenia prevention, highlighting the importance of dietary interventions and other strategies to maintain gut microbiota health. This study was published online in the journal Nutrients on May 21, 2025.
PR TIMES
Moving toward circular agriculture thanks to nutrient separation from manure
Research is underway to develop a circular system for agriculture. Livestock manure contains nutrients such as nitrogen (N), phosphorus (P), and potassium (K), and excessive use of these nutrients can have a negative impact on the environment. As a result, farmers are unable to spread all manure on their land due to environmental regulations and must use synthetic fertilizers as an alternative. However, the production of synthetic fertilizers requires a large amount of energy and has a significant environmental impact.To address this contradiction, researchers are developing methods to separate nitrogen and potassium from manure and convert them into reusable forms. Dr. Marit van der Wal is conducting research using membrane technology to separate these nutrients and enable farmers to use them in precise quantities. This technology is expected to make agriculture sustainable while adhering to environmental regulations.
Phys.org