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DxMedical Cloud™ collects and analyzes professional information from around the world and uses proprietary algorithms to quickly and accurately deliver the information you seek and the best information for you.
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In addition to word matching, the search by similar and related keywords delivers news that is often missed due to paraphrasing and shaky spelling.
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Kyowa Kirin Reacquires Rocatinlimab Development and Commercialization Program, Demonstrating Strong Commitment to High Medical Needs in Atopic Dermatitis
Kyowa Kirin Co., Ltd. has terminated its collaboration agreement with Amgen for rocatinlimab and reacquired full rights to the global program for the drug. Rocatinlimab is a groundbreaking T-cell rebalancing therapy that targets the OX40 receptor on pathogenic T cells, showing potential for long-term disease control in patients with moderate-to-severe atopic dermatitis (msAD). In November 2025, results from the Phase 3 ROCKET trials were published in 'The Lancet', confirming favorable efficacy and safety profiles. Kyowa Kirin plans to first submit for regulatory approval in the United States, followed by Japan and other global markets, aiming to provide a new treatment option for atopic dermatitis patients with high unmet medical needs.
‘Living biosensor’ lights up to detect wine spoilage in real time
Genetically-modified Escherichia coli bacteria that light up in the presence of acetic acid may offer wineries a way to detect wine spoilage in real-time, without the need for specialist equipment.
Unwanted microorganisms found in wine barrels often produce acetic acid as a byproduct of fermentation. A build up of acetic acid stops the conversion of sugars into ethanol and gives wine an unpleasant vinegar-like taste.
Researchers in Israel have now developed a ‘living biosensor’ that luminesces in the presence of acetic acid. The team genetically modified a strain of E. coli with DNA from Bacillus subtilis. When acetic acid levels rise in the fermenting grape juice this activates a pathway in the bacterium that turns on a light producing enzyme known as luciferase.
Menopause linked to Alzheimer's-like brain changes
A large UK study of nearly 125,000 women, including 11,000 MRI brain scans, suggests that menopause is linked to changes in the brain similar to those seen in Alzheimer's disease. Researchers speculate that the loss of grey matter in memory and and emotion-related areas might partly explain why women have a higher risk of dementia than men. The study, published in Psychological Medicine, found that hormone replacement therapy (HRT) did not prevent this grey matter loss. Experts emphasize the need for further research to confirm the link between these brain changes and dementia risk and highlight the importance of mental health support for women during menopause.
iSMART Developments Announces Strategic Partnership with L'Oréal Groupe, Co-developing LED Light Therapy Skincare Devices
UK-based iSMART Developments Ltd. announced a strategic partnership with L'Oréal Groupe, accelerating iSMART's growth in the professional-grade light therapy industry. Together, they co-developed an ultra-thin, flexible silicone "LED Face Mask" and "LED Eye Mask" that emit red and near-infrared light to firm skin and reduce puffiness. Debuted at CES 2026, the collaboration focuses on manufacturing next-generation LED phototherapy devices.
New data suggest enzyme modulator may slow Parkinson’s
Progress in Parkinson’s disease has been judged largely by visible symptoms. Tremors, rigidity, gait changes have been the bellwethers for decades. Beneath those outward signs is a quieter story, one unfolding at the cellular level, where aging neurons struggle to clear toxic buildup and maintain energy balance. New data from AI-powered biotech Gain Therapeutics suggest that the story may finally be measurable and possibly alterable.
In its latest update from a Phase 1b clinical study, Gain Therapeutics reports biomarker evidence that its lead candidate, GT-02287, engages the underlying biology of Parkinson’s disease rather than merely addressing surface-level symptoms [1]. For a field long marked by stalled disease-modifying efforts, the findings offer a cautiously optimistic signal.
The key finding centers on glucosylsphingosine (GluSph), a fatty substance that builds up when an important brain enzyme called glucocerebrosidase (GCase) stops working properly. When GluSph levels rise, it creates a toxic environment inside brain cells, triggering the buildup of harmful proteins, draining cells of energy and disrupting the routine cleanup processes neurons rely on to stay healthy.
BioGAP-Ultra: A Modular Edge-AI Platform for Wearable Multimodal Biosignal Acquisition and Processing
This work introduces BioGAP-Ultra, an advanced, low-power, and flexible wearable multimodal biosensing platform. It enables synchronized acquisition of various electrophysiological and hemodynamic signals (EEG, EMG, ECG, PPG) and supports embedded AI processing with state-of-the-art energy efficiency. BioGAP-Ultra expands on previous designs with increased storage, improved wireless connectivity (up to 1.4 Mbit/s), and more signal modalities (from 3 to 5). It comes with real-time visualization software for mobile phones and demonstrates versatility through integration into different wearable form factors, showcasing edge-AI capabilities like PAT estimation and reach-and-grasp motion classification. Hardware and software design files are open-source.
BlueNalu Announces Insider-Led Convertible Note and Preferred Stock Financings to Advance Commercialization of Cell-Cultivated Bluefin Tuna Toro
BlueNalu, a global leader in the development of cell-cultivated seafood, today announced new convertible note and preferred stock financings. The financings were led by Agronomics, Siddhi Capital, and Lewis & Clark AgriFood, with additional participation from approximately 40 other existing investors. In the financings, BlueNalu secured approximately $11 million in cash and stock proceeds.
Participation to date reflects the continued commitment of BlueNalu’s global investor base and reinforces the company’s leadership position as it advances toward the commercialization of premium, high-value seafood products produced directly from fish cells.
2nd Nature Launches First AI-Discovered Portfolio of Functional Ingredients
2nd Nature, developer of the AgWaste Portal AI platform, has launched its first portfolio of AI-discovered functional ingredients, including non-calorie natural sweeteners and non-sodium umami enhancers. These ingredients, found in the side streams of widely processed crops like wheat, soy, rice, peanut, and corn, are designed to help manufacturers reformulate food and beverage products to reduce sugar and sodium while maintaining taste and functionality. The company has filed a patent for these newly identified compounds, which are expected to be available for commercial sampling in Q2 2026.
Kao unveils innovative sweat transpiration technology for enhanced skin comfort
Kao Corporation has developed an innovative sweat transpiration technology that rapidly spreads and dries sweat to enhance skin comfort, utilizing sweat's natural cooling function rather than suppressing perspiration. Research identified sodium chloride in sweat slowing drying and the interaction of sweat with sebum causing stickiness as key discomfort factors. The developed hydrophilic film reduces the contact angle of sweat droplets, accelerating evaporation, and successfully reduced artificial sweat evaporation time by approximately 33%. Kao plans to develop new cosmetic products based on this technology to alleviate discomfort in hot conditions.
Gas Chromatography-Based Biosensor for Detecting Fruit Ripeness Monitoring the Ripening Process of Stored Fruit
Strella Biotech develops and manufactures gas chromatography-based biosensors that detect fruit ripeness. By installing sensors in controlled atmosphere (CA) storage facilities and monitoring the ripening process of stored fruit, the company helps packers and distributors identify the location of the ripest fruit. This contributes to improved shipping decisions, enhanced inventory management accuracy, and reduced food waste.
Nagoya Institute of Technology Researchers Propose Novel BaTiO3-Based Catalyst for Oxidative Coupling of Methane
Perovskites—a class of compounds with a unique ABX3 structure and high temperature stability—are promising materials for energy conversion. In recent years, they have been utilized in photovoltaic systems. They exhibit excellent performance in solid oxide fuel cells and organic reactions such as oxidative coupling of methane (OCM) for the production of ethane and ethylene.
Researchers demonstrate that BaTiO3, modified with 3 wt% Ca, leads to unique reduced structural motifs on the surface, significantly enhancing the catalytic performance of oxidative coupling of methane in terms of reaction product selectivity
Researchers demonstrate that BaTiO3, modified with 3 wt% Ca, leads to unique reduced structural motifs on the surface, significantly enhancing the catalytic performance of oxidative coupling of methane in terms of reaction product selectivity
Notably, BaTiO3 is a promising perovskite with applications in fields including ferroelectricity, piezoelectricity, and semiconductivity. It possesses a flexible lattice and rich defect chemistry, making it suitable for structural modifications via doping for enhanced functional performance. Furthermore, it offers benefits such as high temperature resistance, cost-effectiveness, and mature industrial-scale production technology.
AGEs Research: From a Quiet Boom to a Solid Trend—A Key Factor for “Healthy Longevity” and “Beauty” That Gained Attention Starting in the 2000s
Flamel Co., Ltd., a company developing and selling supplements, aims to promote a proper understanding of “glycation”—a process deeply involved in aging, lifestyle-related diseases, and beauty—within society. We are committed to helping people achieve a healthy lifestyle they can confidently maintain, not only through supplements but also by reevaluating their diet and daily habits.
As part of this effort, we independently investigated research trends concerning glycation and its final products, Advanced Glycation End-Products (AGEs).
Using PubMed from the U.S. National Institutes of Health (NIH) for data collection (※1), the number of glycation-related papers increased from 375 in 2000 to 2,184 in 2025, representing a roughly sixfold increase over the past 20 years.
The compound annual growth rate (CAGR) since 2000 is estimated at approximately 7.3%, indicating that glycation research is rapidly developing as a new scientific field bridging both “healthy longevity” and “beauty.”
From 3D to AI and Beyond, How Hologic Continues to Shape the Future of Mammography
Hologic was the first to receive FDA approval for a 3D™ mammography (digital breast tomosynthesis) system in 2011. As the company celebrates 40 years of innovation, our team continues to lead the way in breast cancer detection with AI, advanced imaging, and novel technologies that keep the patient front and center.