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Austrian Startup with Plant Fibre-Based Sugar Replacer Zero+ Raises New Funding from German Retail Giant, Accelerating B2B Expansion Across Food Categories
Green Queen (March 16, 2026, by Anay Mridul) reported that Neoh, an Austrian startup that has developed a plant fibre-based low-GI sugar replacer called Zero+, raised several million euros in fresh funding from German retail giant Rewe Group, Zintinus, and Teseo Capital. Founded in 2017 by CEO Manuel Zeller, Neoh developed its technology over 15 years to replace refined sugar with functional dietary fibre. Zero+ is composed of 90% fibre from agave, chicory, and corn, combined with polydextrose, small amounts of erythritol, sucralose, acesulfame K, and natural flavourings. It delivers the same sweetness as table sugar while significantly lowering blood glucose, insulin, and C-peptide levels—confirmed by a 2022 clinical study at the Medical University of Vienna. Per 100g, Zero+ contains 160 calories (a 60% reduction vs. sugar) and 70g of fibre. Its processing properties—flavour, consistency, colour, viscosity, and shelf life—mirror those of sugar, making it industrially scalable. Neoh initially operated as a CPG company selling chocolate bars, wafers, and cookies, but has since shifted to a B2B model supplying Zero+ to manufacturers and retailers. Current partners include Rewe's Billa supermarket chain, Dunkin' Austria, Nom, Anker, Stamag, and Biogena, with applications spanning chocolate biscuits, puddings, breakfast cereals, ice cream, sparkling drinks, and doughnuts. Future development targets protein bars, sauces, jams, and yoghurts. Neoh's 2025 consolidated revenues reached 14M euros (net loss 3M euros), and the company expects sales exceeding 20M euros in 2026. Fibre-rich foods trigger the body's natural GLP-1 response, boosting satiety and regulating blood glucose—an attribute increasingly valued among gut-health-conscious consumers and GLP-1 drug users.
Focusing on Gut Health and Ergothioneine: Health Functionality Research by a Japanese Mushroom Manufacturer
Hokuto, a leading mushroom producer, is advancing research into the health benefits of mushrooms by leveraging the research infrastructure it has built through cultivation techniques and breeding improvements. The company began focusing seriously on research into health benefits around 2000, initially concentrating on research and development for health foods, particularly the immune-boosting effects of Agaricus and the cognitive-enhancing effects of Yamabushitake. Since the 2010s, the company has expanded its research scope to include functional studies on fresh mushrooms such as enoki, maitake, beech mushrooms, and bunapi. In recent years, the company has been particularly focused on the effects of mushrooms on the gut environment. The dietary fiber abundant in mushrooms serves as a nutrient source for gut bacteria and is known to promote the production of short-chain fatty acids. The company’s research confirmed that consuming 50 grams of mushrooms daily for four weeks increased short-chain fatty acids in the gut and showed a tendency toward increased levels of IgA, which plays a role in immunity. Building on these research findings, the company has joined the General Incorporated Foundation for the Promotion of Short-Chain Fatty Acids, which aims to promote the use of short-chain fatty acids, and is actively communicating the health benefits of mushrooms. Another component unique to mushrooms that is attracting attention is ergothioneine, an amino acid with strong antioxidant properties. This compound is rarely found in plants or animals but is abundant in mushrooms, and research is underway on it as a “longevity vitamin.” The company is also conducting clinical trials using oyster mushrooms, which are rich in ergothioneine, to verify their functional benefits, such as skin protection. Mr. Mori, who heads the company’s R&D division, explains, “What sets Hokuto’s R&D apart is our integrated approach, spanning everything from strain development to cultivation. While most mushroom farmers purchase spawn from external sources, we develop our own strains, which has led to the creation of varieties with high functional properties.” The company plans to continue promoting the value of “mushrooms as a health food” while advancing research on the intestinal environment and functional components. Attention is focused on how future research will deepen our understanding of how mushrooms, as a food consumed daily, can contribute to the realization of a society characterized by health and longevity.
California Cultured Bets on $3k Reusable Plastic Bioreactors to Transform Economics of Cultured Cocoa
California Cultured, a startup growing flavanol-rich cocoa via plant cell culture, has completed its first successful commercial production run in a proprietary reusable 2,000-liter plastic bioreactor, announcing in March 2026 that the achievement could transform the economics of cultured cocoa. Rather than scaling up to large centralized stainless steel plants, the company's strategy is to 'scale out' using modular, affordable reactors that cost approximately $3,000 each to build—compared to $500,000–$1,000,000 for a single new stainless steel 2,000-liter bioreactor. The reactors are designed for continuous operation with a proprietary steam sterilization approach that simplifies cleaning and reduces labor inputs, while smart automation systems allow large numbers of reactors to be run with minimal staffing. The company's differentiation rests on three pillars: cell lines selected for traits critical to chocolate (fat production, flavor precursors, and flavanol content); extremely low-capex reactor architecture; and automation software that minimizes labor costs. The first commercial product, a 'cultured cocoa powder,' has been self-affirmed as GRAS and a GRAS notice has been submitted to the FDA. It features zero lead and cadmium with high flavanol levels, intended for use at low inclusion rates as a functional health ingredient to boost the nutritional profile of chocolate products. Commercial product launches with Puratos and Japan's Meiji are expected later in 2026.
Reverse Thinking: “Controlling Bacteria Without Killing Them”—Next-Generation Biofilm Countermeasures Pave the Way for New Sanitation Management
Biofilm, a viscous deposit formed by bacteria, poses significant challenges in plumbing systems and industrial/medical environments, presenting a longstanding issue in hygiene management. CHEMIPAZ Inc.'s anti-biofilm agent demonstrates high efficacy in inhibiting biofilm formation and stripping existing biofilms. Unlike conventional disinfectants, it employs a unique mechanism—previously difficult to commercialize—that acts on bacterial metabolic pathways to inhibit biofilm formation itself. By inhibiting quorum sensing—the communication between bacteria—it suppresses bacterial aggregation and the expression of virulence factors. A key strength is its low risk of creating resistant bacteria, as it does not kill the bacteria themselves. While high cost was a challenge for this technology, the company leveraged its proprietary high-precision biofilm evaluation technology to achieve relatively low-cost material development, leading to commercialization.
Beyond applications in household water areas prone to biofilm formation, it holds promise for diverse uses including food processing plants, medical devices, chemical dilution tanks, and oral care. Alongside the multi-purpose “BR Series,” the company plans to launch the “AF Series” (under development) for surface coating applications. This sustainable hygiene management technology is attracting significant attention.
L'Oréal Partners With Dioxycle To Turn Captured Carbon Into Sustainable Packaging Materials
L'Oréal Groupe has entered a multi-year partnership with clean chemicals startup Dioxycle to convert captured carbon monoxide and carbon dioxide emissions into ethylene—the primary building block of polyethylene—using Dioxycle's carbon electrolysis technology. The electrochemical process, powered by electricity, produces ethylene that performs identically to conventionally derived plastic, enabling a 'drop-in' integration into existing manufacturing systems without requiring infrastructure changes. This addresses one of the beauty industry's most pressing sustainability challenges: packaging materials, largely composed of fossil fuel-derived polyethylene, represent a major share of product-related Scope 3 emissions for multinational consumer goods companies. By sourcing polyethylene from captured industrial carbon, L'Oréal aims to reduce its dependence on petrochemical feedstocks while maintaining the quality standards required for large-scale consumer products. The technology is designed to complement, not replace, other decarbonization strategies such as recycling and bio-based materials, adding a new feedstock stream to diversify plastics production. Dr. Sarah Lamaison, CEO and Co-Founder of Dioxycle, noted that the partnership demonstrates how climate technologies can move from lab innovation to industrial scale, while L'Oréal's SVP of Global Packaging Jacques Playe described it as unlocking new pathways for high-performing, sustainable packaging.
Transforming organizations through 'restoration of humanity' and 'intrinsic motivation'
FICC Inc. and Snow Peak Business Solutions Inc. have co-developed "INSIDE OUT:DOOR," an experiential internal branding support service. This service utilizes outdoor, non-daily environments to foster psychological safety and openness, thereby drawing out "intrinsic motivation" to enhance individual creativity and proactivity, linking corporate purpose with personal missions. The effectiveness of this approach has been demonstrated through joint research with a Keio University professor, aiming to maximize human capital value and cultivate an organizational culture rich in proactivity and creativity.
Is Facial Sagging Caused by 'Bones' Rather Than 'Skin'?
Ortho Co., Ltd. revealed a new understanding that facial sagging is caused not only by skin but also by changes in "bones," based on CT image comparisons, international papers, and surveys. Specifically, bones around the eyes expand and deform with age, and bone density decreases earlier than in the lumbar spine. In response, the company is developing a functional food supplement focused on both skin and bone (containing lycoperoside H, hyaluronic acid, placenta, and soy isoflavones) to offer a new anti-aging care approach that fundamentally re-examines visible changes.
Development of an ultrasonic sensor capable of cuffless, non-invasive blood pressure measurement
A research team led by Dr. Shin Hur at KIMM, in collaboration with KIST, has developed the world's first skin-attachable, non-invasive blood pressure sensor using PMN-PT single-crystal piezoelectric composites and a low-temperature soldering process. This cuffless ultrasonic sensor accurately tracks real-time vascular diameter changes to measure blood pressure within ±4 mmHg, meeting AAMI clinical standards. It is poised to become a core technology for future wearable healthcare devices and smart medical monitoring platforms.
BioGAP-Ultra: A Modular Edge-AI Platform for Wearable Multimodal Biosignal Acquisition and Processing
This work introduces BioGAP-Ultra, an advanced, low-power, and flexible wearable multimodal biosensing platform. It enables synchronized acquisition of various electrophysiological and hemodynamic signals (EEG, EMG, ECG, PPG) and supports embedded AI processing with state-of-the-art energy efficiency. BioGAP-Ultra expands on previous designs with increased storage, improved wireless connectivity (up to 1.4 Mbit/s), and more signal modalities (from 3 to 5). It comes with real-time visualization software for mobile phones and demonstrates versatility through integration into different wearable form factors, showcasing edge-AI capabilities like PAT estimation and reach-and-grasp motion classification. Hardware and software design files are open-source.
ProRx Pharma Redefines Hormone Therapy with Needle-Free Oral Testosterone Option
ProRx Pharma is revolutionizing hormone therapy with the commercial launch of its needle-free oral testosterone formulation. This product offers the same therapeutic effects as injectables without the burden of needles. It safely and significantly expands the reach of hormone replacement therapy (TRT) services for telemedicine, med spas, and clinics, reducing risks such as infections and dosing errors associated with injections. By enhancing patient convenience and adherence, it helps alleviate symptoms related to declining testosterone, including fatigue, muscle loss, and mood changes.
Ultrahuman brings snoring detection and respiratory health tracking to the Ring Air
The Ultrahuman Ring Air now has the capacity to track snoring and general respiratory health. This is thanks to proprietary technology called Respiratory Health PowerPlug, which is basically a suite of audio analysis tools along with some "advanced biomarker tracking" and AI tomfoolery.
All of this results in "one of the most comprehensive consumer tools ever built for understanding nighttime respiratory stability." It details snoring sessions, of course, but also delivers a holistic and "actionable sleep picture." The company says this "reveals patterns, trends and changes in respiratory health over time."
A revolutionary water-based sunscreen technology that frees you from daily stressors like sweat and humidity
Shiseido has developed a new sunscreen technology that, while water-based (Oil in Water type)※1, maintains high water resistance and UV protection. It also adjusts the moisture level on the skin's surface in response to external environmental humidity changes, such as harsh humid heat or dryness caused by air conditioning.
This technology utilizes soap-derived ingredients that react with metal ions found in sweat and seawater. By forming a special structure within the applied film on the skin's surface, it enhances both water repellency and adhesion. While water-based sunscreens are known for their light feel, easy blendability, and minimal stickiness, they tend to wash off easily when exposed to sweat or water. Previously, UV scattering agents and film-forming agents were necessary to improve water resistance. This new formulation achieves a water-resistant film that is lighter than water, flexible, and resistant to creasing. It maintains high water resistance and UV protection while delivering a transparent finish with minimal white residue and reduced transfer onto dark clothing.
Furthermore, Shiseido's research has revealed that sudden humidity changes (environmental shock) activate IL-1α, an inflammatory factor linked to dark spots. This time, by applying technology*2 that spontaneously controls moisture permeability in response to external humidity changes, the product is expected to suppress IL-1α activation. It retains moisture on the skin surface in dry conditions while releasing excess moisture in humid conditions, constantly maintaining a balanced moisture level on the skin surface.
The soap components used in this formulation are optimized for leave-on products, eliminating concerns about soap residue remaining on the skin. Furthermore, the absence of UV scattering agents enhances cleansing efficacy while delivering a moisturized, smooth finish after washing.
California startup tests communication between people in dreams
The founder of a California sleep-technology startup says his team has enabled two people to exchange simple phrases while dreaming, using a wearable device that tracks lucid REM sleep and relays audio signals between participants.
Michael Raduga, CEO of REMspace, told Anadolu that his group spent years attempting to establish dream-to-dream communication.
“Communication in dreams is possible via the phenomenon called lucid dreaming,” he said. “When you have consciousness in REM sleep, you understand what’s going on as if you are in reality, so you can control what you do.”